PD-L1 CRISPR Stable Knockout CT26 Cell Line | T6237

abm | PD-L1 CRISPR Stable Knockout CT26 Cell Line | T6237

PD-L1 and PD-1 form a well-known immune-inhibiting complex that helps prevent the over-activation of the immune system. Studies have shown upregulation of PD-L1 in tumour cells as a countermeasure to suppress immune attacks. However, the extensive molecular mechanism of such interaction has not been thoroughly investigated. PD-L1 CRISPR Stable Knockout CT26 Cell Line presents a useful tool to study PD-1/PD-L1-blocking therapy.

Biosafety:

II

Organism:

Mouse

Source Organ:

Colon

Growth Properties:

Adherent

Morphology:

Epithelial-like

Clones:

N/A

Passage Number:

N/A

Population Doner:

24 - 34 hours

Seeding Density:

N/A

Markers:

PD-L1 knockout

Applications:

For Research Use Only

Doner Gender:

N/A

Donor Ethnicity:

N/A

Knockdown Method:

N/A

Induction:

N/A

Overexpression:

N/A

Freeze Thaw:

N/A

Propagation:

The base medium for this cell line is Prigrow V medium available at abm

Preservation:

1. Freeze Medium: 90% FBS and 10% DMSO.
2. Storage Temperature: Liquid nitrogen vapour phase.

Quality Control:

1) In vitro proliferation assay; 2) Flow cytometry

Tumorgenicn:

N/A

Shipping Conditions:

Dry Ice

Storage Contidions:

-180°C