Recombinant Human AMPK (A1/B1/G1) (C-His tag) | Z500014

abm | Recombinant Human AMPK (A1/B1/G1) (C-His tag) | Z500014

AMPK is a heterotrimer protein kinase consisting of an a catalytic subunit, and non-catalytic ß and ? subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status . In response to cellular metabolic stresses, AMPK is activated and phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating biosynthesis of fatty acid and cholesterol .

Functions:

The specific activity of AMPK was determined to be 737 nmol /min/mg as per activity assay protocol.

Organism:

Human

Source:

Insect cells

Alias:

Subunit A1: PRKAA1, MGC33776, MGC57364 Subunit B1: PRKAB1, AMPK, HAMPKb, MGC17785 Subunit G1: PRKAG1, AMPKG, MGC8666

Gene Symbol:

AMPK (A1/B1/G1)

Gene ID:

N/A

Accession:

NM_006251, NM_006253, NM_002733

Formulation:

50mM NaPhosphate, pH7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.2mM DTT, 25% glycerol.

Solubility:

N/A

Appearance:

Liquid

Molecular Weight (kDa):

68

Molecular Weight 2 (kDA):

38

Molecular Weight 3 (kDA):

40

Purity:

70% - 90%

Concentration:

Shipping Condition :

Dry Ice

Storage Condition:

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.