Recombinant Human AMPK (A1/B1/G3) (C-His tag) | Z500018

abm | Recombinant Human AMPK (A1/B1/G3) (C-His tag) | Z500018

AMPK (A1/B1/G3) is a member of the AMPK family which are heterotrimeric proteins consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPKs are an important energy-sensing enzyme group in the cells that monitor energy status particularly in response to stress . AMPKs regulate fatty acid and cholesterol synthesis by regulating the key rate-limiting enzymes acetyl-CoA carboxylase and hydroxy beta-methylglutaryl-CoA reductase. The ? subunit is dominantly expressed in skeletal muscle where it may play a key role in the regulation of energy metabolism .

Functions:

The specific activity of AMPK was determined to be 185 nmol /min/mg as per activity assay protocol

Organism:

Human

Source:

Insect cells

Alias:

Subunit A1: PRKAA1, MGC33776, MGC57364 Subunit B1: PRKAB1, AMPK, HAMPKb, MGC17785 Subunit G3: PRKAG3

Gene Symbol:

AMPK (A1/B1/G3)

Gene ID:

N/A

Accession:

NM_006251, NM_006253, NM_017431

Formulation:

50mM NaPhosphate, pH7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.2mM DTT, 25% glycerol.

Solubility:

N/A

Appearance:

Liquid

Molecular Weight (kDa):

68

Molecular Weight 2 (kDA):

38

Molecular Weight 3 (kDA):

51

Purity:

70% - 90%

Concentration:

Shipping Condition :

Dry Ice

Storage Condition:

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.