Recombinant Human AMPK (A1/B2/G1) (C-His tag) | Z500020

abm | Recombinant Human AMPK (A1/B2/G1) (C-His tag) | Z500020

AMPK (A1/B2/G1) is a member of the AMPK family which are heterotrimeric proteins consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPKs are an important energy-sensing enzyme group in the cells that monitor energy status particularly in response to stress . AMPKs regulate fatty acid and cholesterol synthesis by regulating the key rate-limiting enzymes acetyl-CoA carboxylase and hydroxy beta-methylglutaryl-CoA reductase. The ß subunit may be a positive regulator of AMPK activity and is highly expressed in skeletal muscle .

Functions:

The specific activity of AMPK was determined to be 349 nmol /min/mg as per activity assay protocol

Organism:

Human

Source:

Insect cells

Alias:

Subunit A1: PRKAA1, MGC33776, MGC57364 Subunit B2: PRKAB2, MGC61468 Subunit G1: PRKAG1, AMPKG, MGC8666

Gene Symbol:

AMPK (A1/B2/G1)

Gene ID:

N/A

Accession:

NM_006251, NM_005399, NM_002733

Formulation:

50mM NaPhosphate, pH7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.2mM DTT, 25% glycerol.

Solubility:

N/A

Appearance:

Liquid

Molecular Weight (kDa):

68

Molecular Weight 2 (kDA):

36

Molecular Weight 3 (kDA):

40

Purity:

70% - 90%

Concentration:

Shipping Condition :

Dry Ice

Storage Condition:

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.