Recombinant Human AMPK (A2/B1/G1) (C-His tag) | Z500023

abm | Recombinant Human AMPK (A2/B1/G1) (C-His tag) | Z500023

AMPK (A2/B1/G1) plays a key role in insulin signaling pathway and is a major therapeutic target for the treatment of diabetes . AMPK is viewed as a fuel sensor for glucose and lipid metabolism by modulating the activity of the autonomous nervous system in vivo. Short-term overexpression of a constitutively active form of AMPK in the liver leads to mild hypoglycemia and fatty liver due to increased fatty acid utilization .

Functions:

The specific activity of AMPK was determined to be 310 nmol /min/mg as per activity assay protocol.

Organism:

Human

Source:

Insect cells

Alias:

Subunits A2: PRKAA2, AMPK, AMPK2, PRKAA Subunit B1: PRKAB1, AMPK, HAMPKb, MGC17785 Subunit G1: PRKAG1, AMPKG, MGC8666

Gene Symbol:

AMPK (A2/B1/G1)

Gene ID:

N/A

Accession:

NM_006252, NM_006253, NM_002733

Formulation:

50mM NaPhosphate, pH7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol.

Solubility:

N/A

Appearance:

Liquid

Molecular Weight (kDa):

69

Molecular Weight 2 (kDA):

38

Molecular Weight 3 (kDA):

40

Purity:

70% - 90%

Concentration:

Shipping Condition :

Dry Ice

Storage Condition:

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.