Recombinant Human BMPR2 (N-His tag) | Z500038

abm | Recombinant Human BMPR2 (N-His tag) | Z500038

BMPR2 is a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs that are involved in endochondral bone formation and embryogenesis . The loss of interaction and lack of phosphorylation of TCTEL1 by BMPR2 may contribute to the pathogenesis of primary pulmonary hypertension (PPH) and BMPR2 also plays an essential role in human T-cell differentiation .

Functions:

The specific activity of BMPR2 was determined to be 14 nmol /min/mg as per activity assay protocol.

Organism:

Human

Source:

Insect cells

Alias:

BMPR-II; BMPR3; BMR2; BRK-3; FLJ41585; FLJ76945; PPH1; T-ALK

Gene Symbol:

BMPR2

Gene ID:

N/A

Accession:

NM_001204

Formulation:

50mM sodium, pHosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol.

Solubility:

N/A

Appearance:

Liquid

Molecular Weight (kDa):

115

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

70% - 90%

Concentration:

Shipping Condition :

Dry Ice

Storage Condition:

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.