Recombinant Human BMX | Z500413

abm | Recombinant Human BMX | Z500413

Recombinant full-length human BMX was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. The BMX gene encodes a non-receptor tyrosine kinase, which may play a role in the growth and differentiation of hematopoietic cells. The BMX gene is located on chromosomal band Xp22.2 between the DXS197 and DXS207 loci. Interestingly, chromosome X also contains the closest relative of BMX, the BTK gene, implicated in X-linked agammaglobulinemia. BMX is found to induce activation of the Stat signalling pathway.

Functions:

The specific activity of BMX was determined to be 34 nmol/min/ml.

Organism:

Human

Source:

Insect Cells

Alias:

Bone marrow tyrosine kinase, ETK, PSCTK2, PSCTK3

Gene Symbol:

BMX

Gene ID:

N/A

Accession:

NM_001721

Formulation:

Recombinant BMX is stored in 50 mM Tris-HCl (pH 7.5), 150 mM NaCl, 0.25 mM DTT, 10 mM glutathione, 0.1 mM EDTA, 0.1 mM PMSF, 25% Glycerol at 0.1 µg/µl.

Solubility:

N/A

Appearance:

Liquid

Molecular Weight (kDa):

110

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

>80% as determined by SDS-PAGE

Concentration:

Shipping Condition :

Dry Ice

Storage Condition:

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.