Recombinant Human CK2 alpha 2 (N-GST tag) | Z500091

abm | Recombinant Human CK2 alpha 2 (N-GST tag) | Z500091

CK2a2 or casein kinase II alpha 2 is a member of the CK2 family of Ser/Thr protein kinases. CK2a2 plays a fundamental role in cell function and is involved in DNA replication, regulation of basal and inducible transcription, translation and control of metabolism. CK2a2 prefers utilization of acidic proteins such as caseins as substrates. The CK2a2 holoenzyme is a tetramer composed of an alpha chain, an alpha' and two beta chains. The alpha and alpha' chains contain the catalytic site. CK2a2 is also a component of CK2-SPT16-SSRP1 complex comprised of SSRP1, SUPT16H, CSNK2A1, CSNK2A2 and CSNK2B . This complex associates following UV irradiation. CK2a2 act as a candidate gene for inherited abnormalities of sperm morphogenesis .

Functions:

The specific activity of CK2a2 was determined to be 63 nmol /min/mg as per activity assay protocol.

Organism:

Human

Source:

Insect cells

Alias:

CSNK2A2; CKII-alpha 2; CK2A2

Gene Symbol:

CK2a2

Gene ID:

N/A

Accession:

NM_001896

Formulation:

50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

Solubility:

N/A

Appearance:

Liquid

Molecular Weight (kDa):

64

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

70% - 90%

Concentration:

Shipping Condition :

Dry Ice

Storage Condition:

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.