Recombinant Human CTGF | Z102025

abm | Recombinant Human CTGF | Z102025

Secreted by vascular endothelial cells, CTGF is a regulatory protein that has been shown to stimulate the growth of chondrocytes, promote angiogenesis and mediate cell adhesion of fibroblasts and endothelial cells. The binding of CTGF to heparin induces cell migration and adhesion. Mature Human CTGF is a 38.0 kDa secreted protein that is comprised of four distinct structural domains (a) IGFBP N-terminal domain (b) VWFC domain (c) TSP type-I domain and (d) C-terminal CTCK domain. Recombinant Human CTGF is an 11.3 kDa protein monomeric protein that maps to the CTCK domain.

Functions:

Determined by the dose-dependent stimulation of the proliferation of HUVEC cells. The expected ED50 for this effect is 1.0-2.0 µg/ml.

Organism:

Human

Source:

E. coli

Alias:

CTGF, CCN family member 2, Hypertrophic chondrocyte-specific protein 24, HCS24, Insulin-like growth factor-binding protein 8, IBP-8, IGF-binding protein 8, IGFBP-8
Recombinant Human Connective Tissue Growth Factor (CTGF)

Gene Symbol:

CTGF

Gene ID:

1490

Accession:

P29279

Formulation:

Lyophilized from a 0.2µm filtered solution containing 0.1% TFA

Solubility:

A quick spin of the vial followed by reconstitution in sterile distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

Appearance:

Lyophilized Powder

Molecular Weight (kDa):

11,3

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

>95% as determined by SDS-PAGE

Concentration:

<1.0 EU/μg of recombinant protein as determined by the LAL method

Shipping Condition :

Ambient Temperature

Storage Condition:

The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.