abm human recombinant protein
Recombinant Human FLT3 Ligand (FLT3LG) | Z100229
- SKU:
- Z100229
- Availability:
- 5 to 7 Days Shipment
Description
abm | Recombinant Human FLT3 Ligand (FLT3LG) | Z100229
FLT-3 ligand promotes long- term expansion and differentiation of human pro-B cells in the presence of IL-7 or in combination of IL-7 and IL-3. The human flt-3 ligand also stimulates the proliferation of cells expressing murine flt-3 receptors. In combination with SCF and IL3, flt-3 ligand can cause expansion of cells with the marker spectrum CD34(+) CD38(-). Alone, flt- 3 ligand supports the survival of precursors in the lineage of blood-forming cells such as CFU-GM, CFU- GEMM, and the very primitive high proliferative potential colony-forming cells, HPP-CFC. flt-3 ligand only has marginal effects on progenitors for erythroid cells and megakaryocytes.
Functions:
The ED(50) was determined by the dose-dependent stimulation of the proliferation of Human AML5 cells was found to be in the range of 1.0 ng/mL.
Organism:
Human
Source:
E. coli
Alias:
Fms-related tyrosine kinase 3 ligand, Flt3 ligand, FLT3LG, Flt3L, SL cytokine
Gene Symbol:
FLT3LG
Gene ID:
2323
Accession:
P49771
Formulation:
Recombinant FLT-3 Ligand was lyophilized from a 0.2 μm filtered PBS solution pH 7.0.
Solubility:
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Appearance:
Lyophilized Powder
Molecular Weight (kDa):
17
Molecular Weight 2 (kDA):
N/A
Molecular Weight 3 (kDA):
N/A
Purity:
>95% as determined by SDS-PAGE
Concentration:
<1.0 EU/μg of recombinant protein as determined by the LAL method.
Shipping Condition :
Ambient Temperature
Storage Condition:
The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.