abm human recombinant protein
Recombinant Human Fractalkine (CX3CL1) | Z101895
- SKU:
- Z101895
- Availability:
- 5 to 7 Days Shipment
Description
abm | Recombinant Human Fractalkine (CX3CL1) | Z101895
Fractalkine is a type I membrane protein that signals through the CX3CR1 receptor. The extracellular domain of Fractalkine is released by protease cleavage – producing soluble Fractalkine. Fractalkine has been found in many tissues and shown to be up-regulated in endothelial cells and microglia in response to inflammatory signals. Fractalkine is also involved in leukocyte adhesion as well as attracting monocytes, microglia cells and NK cells.
Functions:
Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with mouse CX3CR1. The ED(50) for this effect is typically 20100 ng/mL
Organism:
Human
Source:
E. coli
Alias:
C-X3-C motif chemokine 1, CX3C membrane-anchored chemokine, Neurotactin, Small-inducible cytokine D1
Gene Symbol:
CX3CL1
Gene ID:
6376
Accession:
P78423
Formulation:
Lyophilized from a 0.2μm filtered solution in 20mM phosphate buffer and 50mM NaCl, pH 7.4
Solubility:
A quick spin of the vial followed by reconstitution in sterile distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Appearance:
Lyophilized Powder
Molecular Weight (kDa):
8,9
Molecular Weight 2 (kDA):
N/A
Molecular Weight 3 (kDA):
N/A
Purity:
>95% as determined by SDS-PAGE
Concentration:
<1.0 EU/μg of recombinant protein as determined by the LAL method.
Shipping Condition :
Ambient Temperature
Storage Condition:
The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.