Recombinant Human IKK epsilon (N-GST tag) | Z500178

abm | Recombinant Human IKK epsilon (N-GST tag) | Z500178

IKK epsilon is a noncanonical I-kappa-B kinase (IKK) that is essential for regulating antiviral signaling pathways that has also been identified as a breast cancer oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines . IKK-epsilon is a part of a novel PMA-inducible I-kappa-B kinase complex which play an essential role for an in triggering the host antiviral response to viral infection. IKKE plays a critical role in the IFN-inducible antiviral transcriptional response .

Functions:

The specific activity of IKKe was determined to be 12 nmol /min/mg as per activity assay protocol.

Organism:

Human

Source:

Insect cells

Alias:

IKBKE, IKKE, IKKI, IKK-i, KIAA0151, MGC125294, MGC125295

Gene Symbol:

IKK epsilon

Gene ID:

N/A

Accession:

NM_014002

Formulation:

50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

Solubility:

N/A

Appearance:

Liquid

Molecular Weight (kDa):

110

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

70% - 90%

Concentration:

Shipping Condition :

Dry Ice

Storage Condition:

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.