Recombinant Human IL17D | Z102425

abm | Recombinant Human IL17D | Z102425

Interleukin 17D is a disulfide-linked homodimer belonging to the IL-17 family of proinflammatory cytokines. Members belonging to this family share conserved features of cysteine-knot structures but differ in their N-terminal regions. The T-helper cell produced IL17 family is inducible by IL15 and IL23, and IL17D induces expression of endothelial IL6, IL8, and GM-CSF, and inhibits hemopoiesis of myeloid progenitor cells.

Functions:

The ED50 is 7.5-37.5 ng/mL as determined by its binding ability in a functional ELISA (at a concentration of 1 µg/mL)

Organism:

Human

Source:

E. coli

Alias:

Interleukin-27

Gene Symbol:

IL17D

Gene ID:

53342

Accession:

Q8TAD2

Formulation:

Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA (with BSA as a carrier protein)

Solubility:

Reconstitute in sterile 4mM HCl at 100µg/mL (containing at least 0.1% human or bovine serum albumin)

Appearance:

Lyophilized Powder

Molecular Weight (kDa):

20,5

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

>95% as determined by SDS-PAGE

Concentration:

<1.0 EU/μg of recombinant protein as determined by the LAL method

Shipping Condition :

Ambient Temperature

Storage Condition:

The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.