Recombinant Human IL19 | Z102449

abm | Recombinant Human IL19 | Z102449

IL19 belongs to the IL-10 family of proinflammatory cytokines, which is composed of IL10, IL19, IL20, IL22, IL24, and IL26. IL19 is mainly expressed in monocytes and binds to the IL20 receptor complex which leads to the activation of the signal transducer and activator of transcription 3 (STAT3). It also performs up-regulation of IL6 and TNF-alpha and apoptosis induction, thus signifying its role in inflammatory responses.

Functions:

The ED50 is 0.5-1.5 ng/mL as determined by a cell proliferation assay with the use of transfected BaF3 mouse pro-B cells with human IL-20Rα and human IL-20Rβ

Organism:

Human

Source:

E. coli

Alias:

Melanoma differentiation-association protein-like protein, NG.1

Gene Symbol:

IL19

Gene ID:

29949

Accession:

Q9UHD0

Formulation:

Lyophilized from a 0.2 µm filtered solution in PBS (with BSA as a carrier protein)

Solubility:

Reconstitute in sterile PBS at 10µg/mL (containing at least 0.1% human or bovine serum albumin)

Appearance:

Lyophilized Powder

Molecular Weight (kDa):

18

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

>95% as determined by SDS-PAGE

Concentration:

< 1.0 EU/μg of recombinant protein as determined by the LAL method.

Shipping Condition :

Ambient Temperature

Storage Condition:

The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.