Recombinant Human IL37 (IL1F7) | Z102087

abm | Recombinant Human IL37 (IL1F7) | Z102087

Member of the IL-1 family, IL-37 functions to curb excessive inflammation. In partnership with SMAD3, IL-37 suppresses, or reduces, proinflammatory cytokine production, including IL1A and IL6, as well as CCL12, CSF1, CSF2, CXCL13, IL1B, IL23A and IL1RN, but spares anti-inflammatory cytokines. Out of the five isoforms for IL-37 (a-e), this product represents isoform B that is expressed in testis, colon, placenta, lung and lymph node similar to isoform A and C but is the only one found in kidneys.

Functions:

N.A.

Organism:

Human

Source:

E. coli

Alias:

IL-37, IL-23, FIL1 zeta, IL-1X, Interleukin-1 family member 7, IL-1F7, Interleukin-1 homolog 4, IL-1H, IL-1H4, Interleukin-1 zeta, IL-1 zeta, Interleukin-1-related protein, IL-1RP1
Recombinant Human Interleukin-37/Interleukin-23 (IL37/IL23)

Gene Symbol:

IL37

Gene ID:

27178

Accession:

Q9NZH6

Formulation:

Lyophilized from a 0.2 μm filtered solution in PBS and DTT

Solubility:

Reconstitute at 100 μg/mL in sterile PBS

Appearance:

Lyophilized Powder

Molecular Weight (kDa):

19,5

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

>95% as determined by SDS-PAGE

Concentration:

<1.0 EU/μg of recombinant protein as determined by the LAL method.

Shipping Condition :

Ambient Temperature

Storage Condition:

The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.