Recombinant Human MEC (CCL28) | Z101025

abm | Recombinant Human MEC (CCL28) | Z101025

The mucosa-associated epithelial chemokine CCL28 is a common mucosal chemokine which is constitutively expressed by epithelial cells in most mucosal sites. Both CCL28 and CCL25 have recently been shown to be essential for lymphocyte migration to gastrointestinal tissues. CCL28 attracts IgA ASC, but not IgG or IgM ASC, from both intestinal and extraintestinal mucosal tissue, while CCL25 preferentially attracts IgA ASC from the small intestine and its draining lymphoid tissues, as well as alpha-4-beta-7(+) T cells.

Functions:

Determined by the ability to chemoattract human lymphocytes using a concentration range of 2-10 ng/mL.

Organism:

Human

Source:

E. coli

Alias:

C-C motif chemokine 28, CCL28, MEC, Protein CCK1, Small-inducible cytokine A28, SCYA28
Recombinant Human Mucosae-Associated Epithelial Chemokine (CCL28)

Gene Symbol:

CCL28

Gene ID:

56477

Accession:

Q9NRJ3

Formulation:

Recombinant CCL-28 was lyophilized from PBS pH 7.4.

Solubility:

A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

Appearance:

Lyophilized Powder

Molecular Weight (kDa):

12

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

>95% as determined by SDS-PAGE

Concentration:

<1.0 EU/μg of recombinant protein as determined by the LAL method.

Shipping Condition :

Ambient Temperature

Storage Condition:

Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.