Recombinant Human MMP2 | Z101817

abm | Recombinant Human MMP2 | Z101817

MMP-2 belongs to a family of endoproteases which need calcium and zinc in order to exert their catalytic capability (extracellular matrix remodeling). The elevated expression of these enzymes has been linked to many degenerative disorders, such as arthritis, cancer metastasis and skeletal growth-plate disorders. It has been shown that MMP-2 associates with many connective tissue cells as well as neutrophils, macrophages and monocytes.

Functions:

The ED(50) was determined by the dose-dependent proliferation of immortalized human pulmonary fibroblasts cells and was found to be <0.05ng/mL.

Organism:

Human

Source:

E. coli

Alias:

MMP-2, 72 kDa type IV collagenase, 72 kDa gelatinase, Gelatinase A, TBE-1
Recombinant Human Matrix Metalloproteinase-2 (MMP2)

Gene Symbol:

MMP2

Gene ID:

4313

Accession:

P08253

Formulation:

Supplied as a 0.2 μm filtered solution in Tris, CaCl2, NaCl and Brij­35

Solubility:

N.A.

Appearance:

Lyophilized Powder

Molecular Weight (kDa):

62

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

>95% as determined by SDS-PAGE

Concentration:

< 1.0 EU/μg of recombinant protein as determined by the LAL method.

Shipping Condition :

Ambient Temperature

Storage Condition:

The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.