abm human recombinant protein
Recombinant Human TGF Beta-1 (TGFB1) | Z101555
- SKU:
- Z101555
- Availability:
- 5 to 7 Days Shipment
Description
abm | Recombinant Human TGF Beta-1 (TGFB1) | Z101555
TGFB1 is the prototype member of the TGF-beta super-family that includes Inhibins, Activin A, MIS (Müllerian inhibiting substance), BMP (bone morphogenetic proteins), dpp (decapentaplegic) and Vg-1. TGFB1 is the most potent known growth inhibitor for normal and transformed epithelial cells, endothelial cells, fibroblasts, neuronal cells, lymphoid cells and other hematopoietic cell types. TGF-beta inhibits the proliferation of T lymphocytes by down-regulating predominantly IL2 mediated proliferative signals and also inhibits the growth of natural killer cells. Recombinant human TGFB1 is a disulfide linked homodimer protein that migrates at approximately 26kDa under non-reducing conditions.
Functions:
The ED50 as determined by the ability to inhibit the proliferation of mink lung epithelial cells was found to be in the range of 0.05-0.1 ng/ml
Organism:
Human
Source:
HEK293 cells
Alias:
Transforming growth factor beta-1, TGF-beta-1, Differentiation inhibiting factor, Latency-associated peptide, LAP
Gene Symbol:
TGFB1
Gene ID:
7040
Accession:
P01137
Formulation:
Lyophilized from 0.2 μm filtered PBS solution pH 7.4
Solubility:
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Appearance:
Lyophilized Powder
Molecular Weight (kDa):
26
Molecular Weight 2 (kDA):
N/A
Molecular Weight 3 (kDA):
N/A
Purity:
>95% as determined by SDS-PAGE
Concentration:
<1.0 EU/μg of recombinant protein as determined by the LAL method
Shipping Condition :
Ambient Temperature
Storage Condition:
Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months. Avoid repeated freeze/thaw cycles.