Recombinant Human TRAIL (TNFSF10) | Z101759

abm | Recombinant Human TRAIL (TNFSF10) | Z101759

A cytotoxic protein, TRAIL initiates apoptosis in tumor cells by binding the death-signalling receptors; DR4 and DR5. In its active conformation, TRAIL forms homotrimers. TRAIL transcripts have been shown to be constitutively expressed in a variety of human tissues. There are five known TRAIL receptors: two which transduce apoptotic signals, two which function as decoys to block TRAIL-induced apoptosis and osteoptotegrin.

Functions:

N.A.

Organism:

Human

Source:

E. coli

Alias:

TRAIL, Tumor necrosis factor (Ligand) family member 10, TNFSF10, Apo2 Ligand, TL2
Recombinant Human TNF-Related Apoptosis-Inducing Ligand (TNFSF10)

Gene Symbol:

TNFSF10

Gene ID:

8743

Accession:

P50591

Formulation:

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Solubility:

Reconstitute at 20 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin

Appearance:

Lyophilized Powder

Molecular Weight (kDa):

19,5

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

>95% as determined by SDS-PAGE

Concentration:

< 1.0 EU/μg of recombinant protein as determined by the LAL method.

Shipping Condition :

Ambient Temperature

Storage Condition:

The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.