Recombinant Human TWEAK (TNFSF12) | Z102279

abm | Recombinant Human TWEAK (TNFSF12) | Z102279

TWEAK is a TNF superfamily transmembrane protein which is expressed in many different cells and tissues, such as the heart, spleen and small intestine. Two different receptors have been identified that bind TWEAK; the Death Receptor 3 (DR3) and the TWEAK Receptor (TWEAKR). While DR3 is expressed mainly in tissues that have high concentration of lymphocytes, the mitogen-inducible TWEAKR is has been shown to be expressed in fibroblasts, hepetocellular carcinomas and endothelial cells. Recombinant human TWEAK comprises the TNF homologous (secreted region) of TWEAK.

Functions:

N/A

Organism:

Human

Source:

E. coli

Alias:

TWEAK, Tumor necrosis factor ligand superfamily member 12, TNFSF12, DR3LG, Apo3-Ligand
Recombinant Human TNF-Related Weak Inducer of Apoptosis (TNFSF12)

Gene Symbol:

TNFSF12

Gene ID:

407977

Accession:

O43508

Formulation:

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein

Solubility:

Reconstitute at 0.1mg/ml/mL in sterile PBS containing at least 0.1% human or bovine serum albumin

Appearance:

Lyophilized Powder

Molecular Weight (kDa):

17,2

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

>95% as determined by SDS-PAGE

Concentration:

<1.0 EU/μg of recombinant protein as determined by the LAL method.

Shipping Condition :

Ambient Temperature

Storage Condition:

The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.