Recombinant Mouse IL7 | Z200645

abm | Recombinant Mouse IL7 | Z200645

IL7 is a hematopoietic growth factor constitutively produced by stromal cells from the bone marrow and thymus. It is critical for B and T cell development and survival. IL7 promotes the differentiation of hematopoietic stem cells to lymphoid precursor cells by binding to a receptor composed of common gamma chain and IL-7Ra (CD127). Lymphoid precursor cells give rise to T cells, B cells, and natural killer cells. Furthermore, IL7 provides signals to regulate the survival of naive and memory CD4+ and CD8+ T cells NK T cells, innate lymphoid cells, and T regulatory cells. During B-cell development, IL7 also provides signals to promote survival, proliferation and differentiation. Recombinant mouse IL7 is a non-glycosylated protein with a molecular mass of 15.2 kDa.

Functions:

N/A

Organism:

Mouse

Source:

E. coli

Alias:

Interleukin-7

Gene Symbol:

IL7

Gene ID:

16196

Accession:

N/A

Formulation:

Lyophilized from a 0.2 μm filtered solution in PBS and 2% trehalose, pH 7.4

Solubility:

A quick spin of the vial followed by reconstitution in sterile distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

Appearance:

Lyophilized Powder

Molecular Weight (kDa):

N/A

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

>95% as determined by SDS-PAGE

Concentration:

<1.0 EU/μg of recombinant protein as determined by the LAL method

Shipping Condition :

Ambient Temperature

Storage Condition:

This protein can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.