Recombinant Mouse LIX (CXCL5) | Z200557

abm | Recombinant Mouse LIX (CXCL5) | Z200557

Epithelial neutrophil- activating protein 78 (ENA-78) is a member of the CXC chemokines and acts as a potent chemoattractant and activator of neutrophil function. On stimulation in vitro, ENA-78 is highly expressed in many cell types. ENA-78 protein levels are strongly elevated in synovial fluid and blood of patients with rheumatoid arthritis. By in situ hybridization and immunofluorescence staining, ENA-78 has been recognized as a major CXC chemokine expressed in epithelial cells of the intestinal mucosa of patients with Crohn's disease, ulcerative colitis, and acute appendicitis.

Functions:

Determined by its ability to chemoattract human neutrophils using a concentration range of 2.0-40 ng/mL.

Organism:

Mouse

Source:

E. coli

Alias:

C-X-C motif chemokine 5, Cytokine LIX, Small-inducible cytokine B5

Gene Symbol:

CXCL5

Gene ID:

20311

Accession:

P50228

Formulation:

Lyophilized from a 0.2 µm filtered solution in 20 mM PB,100 mM NaCl pH 7.5.

Solubility:

A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

Appearance:

Lyophilized Powder

Molecular Weight (kDa):

11

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

>95% as determined by SDS-PAGE

Concentration:

<1.0 EU/μg of recombinant protein as determined by the LAL method.

Shipping Condition :

Ambient Temperature

Storage Condition:

The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.