Recombinant Mouse NEK1 (N-GST tag) | Z600018

abm | Recombinant Mouse NEK1 (N-GST tag) | Z600018

NEK1 or NIMA (never in mitosis gene a)-related kinase 1 is a serine/threonine kinase involved in cell cycle regulation and is found in a centrosomal complex with FEZ1, a neuronal protein that plays a role in axonal development. NEK1 is involved early in the DNA damage response pathway . NEK1 cycles through the nucleus via its nuclear localization and export signals . NEK1 protein participates in different signaling pathways to regulate diverse cellular processes and plays an important role in the kidney where it has opened a new avenue for studying cystogenesis and identifying possible modes of therapy.

Functions:

The specific activity of NEK1 was determined to be 70 nmol /min/mg as per activity assay protocol.

Organism:

Mouse

Source:

Insect cells

Alias:

D8Ertd790e; kat; MGC189817

Gene Symbol:

NEK1

Gene ID:

N/A

Accession:

NM_175089

Formulation:

50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

Solubility:

N/A

Appearance:

Liquid

Molecular Weight (kDa):

85

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

70% - 90%

Concentration:

Shipping Condition :

Dry Ice

Storage Condition:

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.