Recombinant Mouse TTBK2 (N-GST tag) | Z600027

abm | Recombinant Mouse TTBK2 (N-GST tag) | Z600027

TTBK2 or tau tubulin kinase 2 is a serine-threonine kinase that putatively phosphorylates tau and tubulin proteins. TTBK2 is a member of the casein kinase (CK1) group of eukaryotic protein kinases that is involved in tau phosphorylation and aggregation . Mutations in TTBK2 cause spinocerebellar ataxia type 11 (SCA11) (a neurodegenerative disease characterized by progressive ataxia and atrophy of the cerebellum and brainstem) .

Functions:

The specific activity of TTBK2 was determined to be 370 nmol /min/mg as per activity assay protocol.

Organism:

Mouse

Source:

Insect cells

Alias:

mKIAA0847; TTBK; TTBK1; TTK

Gene Symbol:

TTBK2

Gene ID:

N/A

Accession:

NM_080788

Formulation:

50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

Solubility:

N/A

Appearance:

Liquid

Molecular Weight (kDa):

88

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

70% - 90%

Concentration:

Shipping Condition :

Dry Ice

Storage Condition:

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.