Recombinant Porcine LIF | Z400015

abm | Recombinant Porcine LIF | Z400015

LIF is a multifunctional secreted glycoprotein that exists in both soluble and matrix bound forms. It displays biologic activities ranging from the differentiation of myeloid leukemic cells into macrophage lineage to effects on bone metabolism, inflammation, neural development, embryogenesis, and the maintenance of implantation. It is now clear that LIF is related in both structure and mechanism of action to the interleukin IL6 family of cytokines, which also includes IL11, ciliary neurotrophic factor, oncostatin M, and cardiotrophin 1. The actions of these cytokines are mediated through specific cell-surface receptors that consist of a unique chain and the shared signal transducing subunit gp130.

Functions:

N/A

Organism:

Rat

Source:

E. coli

Alias:

LIF, Differentiation-stimulating factor, D factor, Melanoma-derived LPL inhibitor (MLPLI) Recombinant Porcine Leukemia Inhibitory Factor (LIF)

Gene Symbol:

LIF

Gene ID:

399503

Accession:

Q9GKZ8

Formulation:

Lyophilized from a 0.2 μm filtered PBS pH 7.0

Solubility:

A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

Appearance:

Lyophilized Powder

Molecular Weight (kDa):

20

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

>95% as determined by SDS-PAGE

Concentration:

<1.0 EU/μg of recombinant protein as determined by the LAL method

Shipping Condition :

Ambient Temperature

Storage Condition:

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favourable performance, avoid repeated handling and multiple freeze/thaw cycles.