GNAO1 Stably Expressing Immortalized Human Mammary Epithelial Cell Line | T6201
- 5 to 7 Days Shipment
abm | GNAO1 Stably Expressing Immortalized Human Mammary Epithelial Cell Line | T6201
GNAO1 Stably Expressing Immortalized Human Mammary Epithelial Cell line expresses GNAO1, the protein of which represent the alpha subunit of the G0 heterotrimeric G-protein signal-transducing complex and is partially responsible for smooth muscle contraction and depressing neuronal activity. They function to inhibit of adenylate cyclase , open K+-channels (via β/γ subunits), and close Ca2+-channels. Researchers may use this cell line to study G-protein signal-transducing pathways in humans. Defects in the GNAO1 gene are known as a cause of early-onset epileptic encephalopathy. This cell line was made using retrovirus transduction. It carries flag tag and expresses GFP.
For Research Use Only
The base medium for this cell line is Prigrow IV available at abm
10⁶ cells/1.0 ml