Huntingtin 20Q Stable PC12 Cell Line | T6019
- 5 to 7 Days Shipment
abm | Huntingtin 20Q Stable PC12 Cell Line | T6019
Huntington disease (HD) is an autosomally dominant degenerative disorder resulting from polyglutamine expansion (>37units) in the huntingtin gene. The repeat is often localized in the N-terminal region of huntingtin and the resulting N-terminal fragments accumulate in the nucleus and become toxic to the cells.
Thaw entire contents into an appropriate T25 flask as specified in the Propagation instructions.
For Research Use Only
Co-transfection of a pCIS expression vector expressing a partial huntingtin cDNA containing 20 CAG repeats and a pCDNA3 expression vector carrying G418 resistance
The base medium for this cell line is Prigrow III medium available at abm
10⁶ cells/1.0 ml