M3R Stable Expressing HEK293 (M3R-GFP) Cell Line | T6244

abm | M3R Stable Expressing HEK293 (M3R-GFP) Cell Line | T6244

Muscarinic type 3 receptor (M3R) is the primary receptor subtype to promote fluid secretion in salivary acinar cells. Research has shown that anti-M3R autoantibodies (anti-M3R) are potential inhibitors of saliva secretion in Sjögren's syndrome (SjS), however there is currently no anti-M3R detection method established. M3R Stable Expressing HEK293 (M3R-GFP) Cell Line is applicable for studies on SjS. It can also be utilized for studies on chronic fatigue syndrome, and neurology or neural regulation-related studies as M3R is one of the important receptors for parasympathetic neurotransmitter, acetylcholine.

Biosafety:

II

Organism:

Human

Source Organ:

Kidney

Growth Properties:

Adherent

Morphology:

Polygonal

Clones:

N/A

Passage Number:

N/A

Population Doner:

36 hours

Seeding Density:

40,000 - 60,000 cells/cm²

Markers:

N/A

Applications:

For Research Use Only

Doner Gender:

N/A

Donor Ethnicity:

N/A

Knockdown Method:

N/A

Induction:

N/A

Overexpression:

N/A

Freeze Thaw:

N/A

Propagation:

The base medium for this cell line is Prigrow III medium available at abm

Preservation:

1. Freeze Medium: Complete growth medium with 20% FBS and 10% DMSO.
2. Storage Temperature: Liquid nitrogen vapour phase.

Quality Control:

1) Western blot; 2) Immunocytochemistry; 3) In-Cell Western assay

Tumorgenicn:

N/A

Shipping Conditions:

Dry Ice

Storage Contidions:

-180°C