Mutant rFIX Stable Expressing HEK293 Cell Line | T6356

abm | Mutant rFIX Stable Expressing HEK293 Cell Line | T6356

Derived from HEK293 cells, Mutant rFIX Stable Expressing HEK293 Cell Line was transfected to stably express the p.R294Q variant of human coagulation factor IX (FIX). p.R294Q is a common FIX missense mutation associated with moderate to severe type I hemophilia B. This mutation functionally impairs FIX, resulting in decreased activity and antigen levels.

Biosafety:

II

Organism:

Human (H. sapiens)

Source Organ:

Kidney

Growth Properties:

Adherent

Morphology:

Epithelial

Clones:

N/A

Passage Number:

N/A

Population Doner:

30 - 40 hours

Seeding Density:

30,000 - 50,000 cells/cm²

Markers:

p.R294Q variant of human coagulation factor IX (FIX; F9 cDNA, reference NM_000133.3)

Applications:

For Research Use Only

Doner Gender:

N/A

Donor Ethnicity:

N/A

Knockdown Method:

N/A

Induction:

N/A

Overexpression:

N/A

Freeze Thaw:

N/A

Propagation:

The base medium for this cell line is Prigrow IV medium available at abm

Preservation:

1. Freeze Medium: 90% FBS and 10% DMSO.
2. Storage Temperature: Liquid nitrogen vapour phase.

Quality Control:

N/A

Tumorgenicn:

N/A

Shipping Conditions:

Dry Ice

Storage Contidions:

-180°C