Recombinant Human ALK3 (BMPR1A) (N-GST tag) | Z500011

abm | Recombinant Human ALK3 (BMPR1A) (N-GST tag) | Z500011

BMPR1A (also known as bone morphogenetic protein receptor 1A) is a member of the transmembrane serine/threonine kinase family that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. BMPR1A act as a minor susceptibility gene for PTEN-mutation-negative Cowden syndrome. BMPR1A regulates the PTEN protein levels by decreasing PTEN's association with the degradative pathway . BMPR1A trafficking plays a significant role in FOP pathogenesis and is also involved in human T-cell differentiation .

Functions:

The specific activity of ALK3 (BMPR1A) was determined to be 1.2 nmol /min/mg as per activity assay protocol.

Organism:

Human

Source:

Insect cells

Alias:

ALK3; BMPR1A; 10q23del; ACVRLK3; CD292; SKR5

Gene Symbol:

ALK3 (BMPR1A)

Gene ID:

N/A

Accession:

NM_004329

Formulation:

50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

Solubility:

N/A

Appearance:

Liquid

Molecular Weight (kDa):

66

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

70% - 90%

Concentration:

Shipping Condition :

Dry Ice

Storage Condition:

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.