Recombinant Human AREG | Z101879

abm | Recombinant Human AREG | Z101879

Amphiregulin is a trans-membrane protein whose protease mediated digestion of the extracellular domain enables release of mature AR. Amphiregulin works to stimulate the proliferation of some animal keratinocyles, epithelial cells and fibroblasts. It has been shown that the mRNA expression of amphiregulin can be detected in numerous carcinoma cell lines and the epithelial cells of various human tissues, including colon, stomach, breast, ovary and kidney.

Functions:

Measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells. The ED(50) for this effect is typically 5­15 ng/mL.

Organism:

Human

Source:

E. coli

Alias:

AR, Colorectum cell-derived growth factor, CRDGF
Recombinant Human Amphiregulin (AREG)

Gene Symbol:

AREG

Gene ID:

374

Accession:

P15514

Formulation:

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein

Solubility:

Reconstitute at 100 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin

Appearance:

Lyophilized Powder

Molecular Weight (kDa):

11,5

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

>95% as determined by SDS-PAGE

Concentration:

<1.0 EU/μg of recombinant protein as determined by the LAL method.

Shipping Condition :

Ambient Temperature

Storage Condition:

The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.