Recombinant Human AXL (N-His tag) | Z500036

abm | Recombinant Human AXL (N-His tag) | Z500036

AXL is a member of the receptor tyrosine kinase family which has oncogenic potential and is implicated in human myeloid leukemia . AXL is a member of a complex signaling network that is involved in the control of cell proliferation and differentiation. Overexpression of AXL cDNA in NIH 3T3 cells induces neoplastic transformation of these cells with the concomitant appearance of a 140kDa AXL tyrosine-phosphorylated protein . Expression of AXL cDNA in the baculovirus system results in the expression of the appropriate recombinant protein that is recognized by antiphosphotyrosine antibodies, confirming that the AXL protein is tyrosine phosphorylated.

Functions:

The specific activity of AXL was determined to be 104 nmol /min/mg as per activity assay protocol

Organism:

Human

Source:

Insect cells

Alias:

UFO, JTK11

Gene Symbol:

AXL

Gene ID:

N/A

Accession:

NM_021913

Formulation:

50mM NaPhosphate, pH7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.2mM DTT, 25% glycerol.

Solubility:

N/A

Appearance:

Liquid

Molecular Weight (kDa):

55

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

70% - 90%

Concentration:

Shipping Condition :

Dry Ice

Storage Condition:

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.