Recombinant Human CAMKK2 (N-GST tag) | Z500059

abm | Recombinant Human CAMKK2 (N-GST tag) | Z500059

CAMKK2 (CAMKKß) is a member of the CAMKK family. It is broadly distributed in tissues with highest levels in brain, thymus, spleen, and testis . CaMKK2 undergoes intramolecular autophosphorylation, is regulated by Ca2+/calmodulin and phosphorylates CaMKI and CaMKIV on Thr177 and Thr200, respectively. CaMKK2 activates both CaMKI and CaMKIV when coexpressed in Jurkat T cells. CaMKK2 also phosphorylates and regulates the activity of AMPK, which is an important regulator of cellular metabolism in response to metabolic stress .

Functions:

The specific activity of CAMKK2 was determined to be 11 nmol /min/mgas per activity assay protocol.

Organism:

Human

Source:

Insect cells

Alias:

CAMKK; CAMKKB; KIAA0787; MGC15254

Gene Symbol:

CAMKK2

Gene ID:

N/A

Accession:

NM_172226

Formulation:

50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.

Solubility:

N/A

Appearance:

Liquid

Molecular Weight (kDa):

88

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

70% - 90%

Concentration:

Shipping Condition :

Dry Ice

Storage Condition:

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.