Recombinant Human CDC42BPG (DMPK2) (N-GST tag) | Z500061

abm | Recombinant Human CDC42BPG (DMPK2) (N-GST tag) | Z500061

Serine/threonine-protein kinase MRCK?, encoded by CDC42BPG gene, acts as a downstream effector of CDC42 in cytoskeletal reorganization, and contributes to the actomyosin contractility required for cell invasion, through the regulation of MYPT1 and MLC2 phosphorylation. It belongs to AGC protein kinase family, DMPK subfamily. It contains an N-terminal kinase domain, followed by a coiled-coil domain, a second coiled-coil domain containing a kinase inhibitory motif (KIM), a variable region, a cysteine-rich domain, a pleckstrin (PLEK; 173570) homology (PH) domain, a citron (605629) homology (CNH) domain, and a C-terminal CDC42 (116952)/RAC (602048) interactive binding (CRIB) domain.

Functions:

The specific activity of CDC42BPG (DMPK2) was determined to be 82 nmol /min/mg as per activity assay protocol.

Organism:

Human

Source:

Insect cells

Alias:

DMPK2; HSMDPKIN; KAPPA-200; MRCKG; MRCKgamma

Gene Symbol:

CDC42BPG (DMPK2)

Gene ID:

N/A

Accession:

NM_017525

Formulation:

50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

Solubility:

N/A

Appearance:

Liquid

Molecular Weight (kDa):

78

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

70% - 90%

Concentration:

Shipping Condition :

Dry Ice

Storage Condition:

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.