Recombinant Human CDC7/DBF4 (N-GST tag) | Z500062

abm | Recombinant Human CDC7/DBF4 (N-GST tag) | Z500062

CDC7 is a cell division cycle 7 homolog protein that is critical for the G1/S transition and is also essential for initiation of DNA replication as cell division occurs. CDC7 is expressed in many normal tissues, but the overexpression of CDC7 may be associated with neoplastic transformation for some tumors and transformed cell lines . CDC7/DBF4 kinase promotes S phase by alleviating an inhibitory activity in Mcm4 that evolved to integrate several protein kinase .

Functions:

The specific activity of CDC7/DBF4 was determined to be 8.5 nmol /min/mg as per activity assay protocol.

Organism:

Human

Source:

Insect cells

Alias:

CDC7: CDC7L1; HsCDC7; Hsk1; huCDC7; MGC117361; MGC126237; MGC126238; DBF4: ASK; CHIF; DBF4A; ZDBF1

Gene Symbol:

CDC7/DBF4

Gene ID:

N/A

Accession:

NM_003503, NM_006716

Formulation:

50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

Solubility:

N/A

Appearance:

Liquid

Molecular Weight (kDa):

94

Molecular Weight 2 (kDA):

125

Molecular Weight 3 (kDA):

N/A

Purity:

70% - 90%

Concentration:

Shipping Condition :

Dry Ice

Storage Condition:

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.