Recombinant Human CDK3/CyclinE1 (N-GST tag) | Z500070

abm | Recombinant Human CDK3/CyclinE1 (N-GST tag) | Z500070

CDK3/CyclinE1is a member of the cyclin-dependent protein kinase family and promotes entry into S phase, in part by activating members of the E2F family of transcription factors. CDK3 can also associate with cyclin C and phosphorylates the retinoblastoma 1 protein to promote exit from G0. The CDK3 gene has been mapped to chromosomal location of 17q22-qter, telomeric to the BRCA1 gene by somatic cell hybrids analysis . The presence of a single point mutation in the CDK3 gene from several Mus musculus strains commonly used in the laboratory has been reported .

Functions:

The specific activity of CDK3/CyclinE1 was determined to be 20 nmol /min/mg as per activity assay protoco

Organism:

Human

Source:

Insect cells

Alias:

CDK3: None CyclinE1: CCNE1, CCNE

Gene Symbol:

CDK3/cyclinE1

Gene ID:

N/A

Accession:

NM_001258, NM_001238

Formulation:

50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.

Solubility:

N/A

Appearance:

Liquid

Molecular Weight (kDa):

60

Molecular Weight 2 (kDA):

73

Molecular Weight 3 (kDA):

N/A

Purity:

70% - 90%

Concentration:

Shipping Condition :

Dry Ice

Storage Condition:

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.