Recombinant Human CDK9/CyclinT2 (N-GST tag) | Z500079

abm | Recombinant Human CDK9/CyclinT2 (N-GST tag) | Z500079

CDK9/Cyclin T2 is a member of the cyclin-dependent protein kinase (CDK) family which are known to be important regulators of cell cycle progression. Cyclin T2 and its kinase partner CDK9 are found to be subunits of the transcription elongation factor p-TEFb. The p-TEFb complex containing this cyclin has been reported to interact with, and act as a negative regulator of human immunodeficiency virus type 1 (HIV-1) Tat protein . The transcription-dependent interaction of P-TEFb with 7SK may therefore contribute to an important feedback loop modulating the activity of RNA Pol II .

Functions:

The specific activity of CDK9/CyclinT2 was determined to be 6 nmol /min/mg as per activity assay protocol.

Organism:

Human

Source:

Insect cells

Alias:

CDK9: CDC2L4, C-2k, TAK, PITALRE CyclinT2: CCNT2; CYCT2

Gene Symbol:

CDK9/CyclinT2

Gene ID:

N/A

Accession:

NM_001261 , NM_001241

Formulation:

50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

Solubility:

N/A

Appearance:

Liquid

Molecular Weight (kDa):

68

Molecular Weight 2 (kDA):

105

Molecular Weight 3 (kDA):

N/A

Purity:

70% - 90%

Concentration:

Shipping Condition :

Dry Ice

Storage Condition:

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.