Recombinant Human DAPK3 (N-GST tag) | Z500101

abm | Recombinant Human DAPK3 (N-GST tag) | Z500101

DAPK3 or Death-associated protein kinase 3 (also known as ZIP) plays a role in apoptosis . DAPK3 is a nuclear serine/threonine-specific kinase that phosphorylates core histones H3 and H4, and myosine light chain in vitro. DAPK3 interacts with transcription and splicing factors as well as with pro-apoptotic protein Par-4 suggesting that it participates in multiple cellular processes. DAPK3 contains a leucine zipper structure at its C terminus and this region is responsible for binding to ATF4. The leucine zipper domain is necessary for the homodimerization of DAPK3 as well as for the activation of the kinase .

Functions:

The specific activity of DAPK3was determined to be 37 nmol /min/mg as per activity assay protocol.

Organism:

Human

Source:

Insect cells

Alias:

ZIP, ZIPK, FLJ36473

Gene Symbol:

DAPK3

Gene ID:

N/A

Accession:

NM_001348

Formulation:

50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.

Solubility:

N/A

Appearance:

Liquid

Molecular Weight (kDa):

79

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

70% - 90%

Concentration:

Shipping Condition :

Dry Ice

Storage Condition:

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.