Recombinant Human DYRK2 (N-GST tag) | Z500110

abm | Recombinant Human DYRK2 (N-GST tag) | Z500110

DYRK2 (also known as dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2) belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and/or development and is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine residues. DYRK2 expressed in E. coli demonstrated tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B in vitro . DYRK2 also regulates p53 to induce apoptosis in response to DNA damage .

Functions:

The specific activity of DYRK2 was determined to be1,250 nmol /min/mg as per activity assay protocol.

Organism:

Human

Source:

Insect cells

Alias:

FLJ21217; FLJ21365

Gene Symbol:

DYRK2

Gene ID:

N/A

Accession:

NM_006482

Formulation:

50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

Solubility:

N/A

Appearance:

Liquid

Molecular Weight (kDa):

95

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

70% - 90%

Concentration:

Shipping Condition :

Dry Ice

Storage Condition:

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.