Recombinant Human EPHB2 (611-893aa) (N-GST tag) | Z500127

abm | Recombinant Human EPHB2 (611-893aa) (N-GST tag) | Z500127

EPHB2 is a member of the Eph family of receptor tyrosine kinases that mediate neurodevelopmental processes such as boundary formation, axon guidance, vasculogenesis, and cell migration. EPHB2 has been shown to associate with the non-receptor tyrosine kinase Abl and activated EPHB2 causes tyrosine phosphorylation of Abl and regulates its activity . EPHB2 is overexpressed in a number of tumors particularly glioblastoma and this increases glioma cell migration and invasion .

Functions:

The specific activity of EPHB2 was determined to be220 nmol /min/mg as per activity assay protocol.

Organism:

Human

Source:

Insect cells

Alias:

DRT, ERK, Hek5, EPHT3, Tyro5, CAPB, PCBC

Gene Symbol:

EPHB2

Gene ID:

N/A

Accession:

NM_004442

Formulation:

50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

Solubility:

N/A

Appearance:

Liquid

Molecular Weight (kDa):

56

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

70% - 90%

Concentration:

Shipping Condition :

Dry Ice

Storage Condition:

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.