Recombinant Human FGF6 | Z101685

abm | Recombinant Human FGF6 | Z101685

FGF-6 is a heparin binding protein of the FGF family which works to control cell division, differentiation, and function. These proteins are especially prominent during prenatal development and postnatal growth. It has been shown that FGF-6 functions as a mitogen for fibroblasts, vascular endothelial cells, and prostate carcinoma cells (N-linked glycosylation is required for the full mitogenic effect). It has also been shown that FGF-6 inhibits the terminal differentiation of myoblasts, cooperates with TGF-2-beta to promote chondrogenesis in embryonic somites, and is present in leukemia cell lines which may undergo platelet megakaryocytic differentiation.

Functions:

Measured in a cell proliferation assay using NR6R-3T3 mouse fibroblast cells

Organism:

Human

Source:

E. coli

Alias:

FGF-6, Heparin secretory-transforming protein 2, HST-2, HSTF-2, Heparin-binding growth factor 6, HBGF-6
Recombinant Human Fibroblast Growth Factor 6 (FGF6)

Gene Symbol:

FGF6

Gene ID:

2251

Accession:

P10767

Formulation:

Lyophilized from a 0.2µm filtered solution in 10mM sodium phosphate and 50mM NaCl, pH 7.5

Solubility:

A quick spin of the vial followed by reconstitution in sterile distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

Appearance:

Lyophilized Powder

Molecular Weight (kDa):

19

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

>95% as determined by SDS-PAGE

Concentration:

< 1.0 EU/μg of recombinant protein as determined by the LAL method.

Shipping Condition :

Ambient Temperature

Storage Condition:

The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.