Recombinant Human Follistatin (FST) | Z101035

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SKU:
Z101035
Availability:
5 to 7 Days Shipment
€267.80
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Description

abm | Recombinant Human Follistatin (FST) | Z101035

Expressed in the pituitary, ovaries, and in some other tissues, FST is a high affinity activin binding protein that can act as an activin antagonist. FST was originally discovered through its suppressive effect of the expression and secretion of the pituitary follicle stimulating hormone. Besides activin, FS has also been shown to bind with multiple BMPs, Myostatin, GDF-11, and TGF-beta-1. Human Follistatin contains three cysteine-rich domains (called Follistatin-like domains), 3 Kazal-like domains and one TGF-beta binding domain.

Functions:

The ED(50) was determined by the ability to neutralize Activin A inhibitory effect of mouse MPC-11 cells and was determined to be 0.1-0.4 µg/mL in the presence of 7.5 ng/mL Activin A.

Organism:

Human

Source:

E. coli

Alias:

FS, Activin-binding protein

Gene Symbol:

FST

Gene ID:

10468

Accession:

P19883

Formulation:

Recombinant Human Follistatin was lyophilized at 1.0 mg/mL containing no additives.

Solubility:

A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

Appearance:

Lyophilized Powder

Molecular Weight (kDa):

31

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

>95% as determined by SDS-PAGE

Concentration:

<1.0 EU/μg of recombinant protein as determined by the LAL method.

Shipping Condition :

Ambient Temperature

Storage Condition:

The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

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Additional Information

Size:
10 µg
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