Recombinant Human GDF3 | Z101735

abm | Recombinant Human GDF3 | Z101735

GDF-3 is a growth and differentiation factor which belongs to the TGF-beta superfamily. GDF-3 and GDF-9 are the only two members of the family which do not form disulfide-linked dimers. GDF-3 has been found in adult bone marrow, spleen, thymus, and adipose tissue. Although signaling in all other members of the family involve the BMP receptors ALK1,2,3, and 6, GDF-3 signals through BMP receptors ALK4 and 7.

Functions:

Measured by its ability to induce Smad2 phosphorylation in P19 mouse embryonal carcinoma cells.

Organism:

Human

Source:

E. coli

Alias:

GDF-3
Recombinant Human Growth Differentiation Factor 3 (GDF3)

Gene Symbol:

GDF3

Gene ID:

9573

Accession:

Q9NR23

Formulation:

Lyophilized from solution in 30mM Acetate buffer, pH 4

Solubility:

Reconstitute at 0.1mg/mL in 4 mM HCl containing at least 0.1% human or bovine serum albumin.

Appearance:

Lyophilized Powder

Molecular Weight (kDa):

13

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

>95% as determined by SDS-PAGE

Concentration:

<1.0 EU/μg of recombinant protein as determined by the LAL method.

Shipping Condition :

Ambient Temperature

Storage Condition:

The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.