Recombinant Human IL28B (IFNL3) | Z101285

abm | Recombinant Human IL28B (IFNL3) | Z101285

Cytokine with immunomodulatory activity. Up-regulates MHC class I antigen expression. Displays potent antiviral activity. Also displays antitumor activity. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.

Functions:

The activity was determined by a WISH cell viral resistance assay with a linear range of 4-20 ng/mL.

Organism:

Human

Source:

CHO cells

Alias:

IL-28B, Interferon lambda-3, IFN-lambda-3, Cytokine Zcyto22, Interleukin-28C, IL-28C, ZCYTO22
Recombinant Human Interleukin-28B (IFNL3)

Gene Symbol:

IFNL3

Gene ID:

282617

Accession:

Q8IZI9

Formulation:

Recombinant Human Interleukin-28B was lyophilized from a 0.2 μm filtered PBS solution pH 7.4.

Solubility:

A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

Appearance:

Lyophilized Powder

Molecular Weight (kDa):

23

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

>95% as determined by SDS-PAGE

Concentration:

<1.0 EU/μg of recombinant protein as determined by the LAL method.

Shipping Condition :

Ambient Temperature

Storage Condition:

The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.