Recombinant Human IRAK2 (N-GST tag) | Z500180

abm | Recombinant Human IRAK2 (N-GST tag) | Z500180

Interleukin-1 receptor-associated kinase 2 (IRAK2) is important downstream signaling components of Toll-like receptors (TLRs) . IRAKs were first described as signal transducers for IL-1 and later have been implicated in signal transduction of other members of the Toll/IL-1 receptor family. The interleukin-1 receptor (IL-1R) signaling pathway leads to NF?B activation in mammals. To date, four mammalian IRAKs have been identified (IRAK-1, IRAK-2, IRAK-4, and IRAK-M) . It is believed that IRAK-2 could be an additional therapeutic target for inhibiting IL-1-induced inflammation.

Functions:

The specific activity of IRAK2 was determined to be6 nmol /min/mg as per activity assay protocol.

Organism:

Human

Source:

Insect cells

Alias:

IRAK-2, MGC150550

Gene Symbol:

IRAK2

Gene ID:

N/A

Accession:

NM_001570

Formulation:

50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

Solubility:

N/A

Appearance:

Liquid

Molecular Weight (kDa):

103

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

70% - 90%

Concentration:

Shipping Condition :

Dry Ice

Storage Condition:

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.