Recombinant Human LIMK1 (N-GST tag) | Z500198

abm | Recombinant Human LIMK1 (N-GST tag) | Z500198

LIMK1 or LIM domain kinase 1 contains a unique combination of 2 N-terminal LIM domain and a C-terminal protein kinase domain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers that can bind to DNA/RNA as well as mediating protein-protein interactions . LIMK1 is thought to be a component of an intracellular signaling pathway that may be involved in brain development especially development of nerve cells. LIMK1 may play an important role in areas of the brain that are responsible for processing visual-spatial information (visuospatial constructive cognition). LIMK1 can regulate aspects of the cytoskeleton, the structural framework that helps to determine cell shape, size, and movement .

Functions:

The specific activity of LIMK1 was determined to be8 nmol /min/mg as per activity assay protocol.

Organism:

Human

Source:

Insect cells

Alias:

LIMK, KIZ

Gene Symbol:

LIMK1

Gene ID:

N/A

Accession:

NM_002314

Formulation:

50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

Solubility:

N/A

Appearance:

Liquid

Molecular Weight (kDa):

65

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

70% - 90%

Concentration:

Shipping Condition :

Dry Ice

Storage Condition:

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.