Recombinant Human MANF | Z102069

abm | Recombinant Human MANF | Z102069

MANF is a neurotrophic factor found mainly in central nervous tissues where it may remain localized to the endoplasmic reticulum and in the Golgi apparatus, or secreted. It has been shown that MANF plays an important role in protecting cells against tunicamycin and thapsigargin-induced cell death. Without MANF, cells become increasingly vulnerable to the aforementioned drugs. Also, MANF is structurally homologous to CDNF.

Functions:

N.A.

Organism:

Human

Source:

E. coli

Alias:

Arginine-rich protein, Protein ARMET, ARP
Recombinant Human Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF)

Gene Symbol:

MANF

Gene ID:

7873

Accession:

P55145

Formulation:

Lyophilized from a 0.2 μm filtered solution in PBS

Solubility:

Reconstitute at 200 μg/mL in PBS

Appearance:

Lyophilized Powder

Molecular Weight (kDa):

18,4

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

>95% as determined by SDS-PAGE

Concentration:

< 1.0 EU/μg of recombinant protein as determined by the LAL method.

Shipping Condition :

Ambient Temperature

Storage Condition:

The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.