Recombinant Human MATK (CTK) (N-GST tag) | Z500213

abm | Recombinant Human MATK (CTK) (N-GST tag) | Z500213

MATK belongs to tyrosine protein kinase family, CSK subfamily. It inactivates Src family kinase activity by specifically phosphorylating their C-terminal regulatory tyrosine residue and may plays a significant role in the signal transduction of hematopoietic cells . MATK binds to the phosphorylated Tyr568/570 sites on c-KIT to which FYN binds and leads to the down-regulation of FYN . MATK has been shown to be involved in signaling in some cases of breast cancer.

Functions:

The specific activity of MATK (CTK)was determined to be 11nmol /min/mg as per activity assay protocol.

Organism:

Human

Source:

Insect cells

Alias:

CHK; CTK; HHYLTK; HYL; HYLTK; LSK

Gene Symbol:

MATK (CTK)

Gene ID:

N/A

Accession:

NM_139355

Formulation:

50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

Solubility:

N/A

Appearance:

Liquid

Molecular Weight (kDa):

83

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

70% - 90%

Concentration:

Shipping Condition :

Dry Ice

Storage Condition:

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.