Recombinant Human MEK6 (N-GST tag) | Z500217

abm | Recombinant Human MEK6 (N-GST tag) | Z500217

MEK6 or MAP2K6(mitogen-activated protein kinase kinase 6) is a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase that also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. MEK6 phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress . As an essential component of p38 MAP kinase mediated signal transduction pathway, MEK6 is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis .

Functions:

The specific activity of MEK6 was determined to be 570 nmol /min/mg as per activity assay protocol.

Organism:

Human

Source:

Insect cells

Alias:

MAP2K6, MAPKK6, MKK6, PRKMK6, SAPKK3, SKK3, SEK3

Gene Symbol:

MEK6

Gene ID:

N/A

Accession:

BC012009

Formulation:

50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

Solubility:

N/A

Appearance:

Liquid

Molecular Weight (kDa):

64

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

70% - 90%

Concentration:

Shipping Condition :

Dry Ice

Storage Condition:

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.