Recombinant Human MINK1 (N-GST tag) | Z500225

abm | Recombinant Human MINK1 (N-GST tag) | Z500225

MINK1 is a member of the germinal center family of kinases that are homologous to the Ste20 family and regulate a wide variety of cellular processes, including cell morphology, cytoskeletal rearrangement, and survival . Overexpression of kinase-dead mutants of MINK1 leads to enhanced cell spreading, actin stress fiber formation, adhesion to extracellular matrix and decreased cell motility and invasion. MINK is activated after Ras induction via a mechanism involving reactive oxygen species and mediates stimulation of p38 MAPK downstream of the Raf/ERK pathway .

Functions:

The specific activity of MINK1 was determined to be19 nmol /min/mg as per activity assay protocol.

Organism:

Human

Source:

Insect cells

Alias:

B55; ZC3; MINK; YSK2; hMINK; MAP4K6; MGC21111; hMINKß

Gene Symbol:

MINK1

Gene ID:

N/A

Accession:

NM_015716

Formulation:

50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.

Solubility:

N/A

Appearance:

Liquid

Molecular Weight (kDa):

61

Molecular Weight 2 (kDA):

N/A

Molecular Weight 3 (kDA):

N/A

Purity:

70% - 90%

Concentration:

Shipping Condition :

Dry Ice

Storage Condition:

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.